Basic Virology 3/e 2008

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內容簡介

Ideal for the student seeking a solid understanding of the basic principles in this rapidly developing field, this best-selling text offers a comprehensive introduction to the fundamentals of virology. Featuring an enhanced art program now in full-color, the new edition has been updated throughout.

• New edition incorporates additional reading suggestions, expanded review questions, chapter outlines and full-colour artwork

• Contains new chapters dealing with viruses and cancer, generation and use of recombinant viruses and virus-like particles, viral evolution, network biology and viruses, and animal models and transgenics, as well as a chapter devoted to HIV and AIDS

• Downloadable artwork, original animations and online resources are available at www.blackwellpublishing.com/wagner

作者簡介

Edward K. Wagner (May 4, 1940 - January 21, 2006) was Professor of Molecular Biology and Biochemistry at the University of California Irvine. Martinez J. Hewlett is Professor Emeritus in the Department of Molecular and Cellular Biology at the University of Arizona. New to this edition, David C. Bloom is Associate Professor in the Department of Molecular Genetics and Microbiology at University of Florida and David Camerini is Assistant Professor in the Department of Molecular Biology and Biochemistry at the University of California Irvine.

Part I: Virology and Viral Disease.

1. Introduction – the Impact of Viruses on Our View of Life 2.

2. An Outline of Virus Replication and Viral Pathogenesis.

3. Virus Disease in Populations and Individual Animals.

4. Patterns of Some Viral Diseases of Humans.

Part II: Basic Properties of Viruses and Virus–Cell Interaction.

5. Virus Structure and Classification.

6. The Beginning and End of the Virus Replication Cycle.

7. Host Immune Response to Viral Infection – The Nature of the Vertebrate Immune Response.

8. Strategies to Protect Against and Combat Viral Infection.

Part III: Working with Virus.

9. Visualization and Enumeration of Virus Particles.

10. Replicating and Measuring Biological Activity of Viruses.

11. Physical and Chemical Manipulation of the Structural Components of Viruses.

12. Characterization of Viral Products Expressed in the Infected Cell.

13. Viruses Use Cellular Processes to Express Their Genetic Information.

Part IV: Replication Patterns of Specific Viruses.

14. Replication of Positive-sense RNA Viruses.

15. Replication Strategies of RNA Viruses Requiring RNA-directed mRNA Transcription as the First Step in Viral Gene Expression.

16. Replication Strategies of Small and Medium-sized DNA Viruses.

17. Replication of Some Nuclear-replicating Eukaryotic DNA Viruses with Large Genomes.

18. Replication of Cytoplasmic DNA Viruses and “Large” Bacteriophages.

19. Retroviruses: Converting RNA to DNA.

20. Human Immunodeficiency Virus Type 1 (HIV-1) and Related Lentiviruses.

21. Hepadnaviruses: Variations on the Retrovirus Theme.

Part V: Viruses: New Approaches and New Problems.

22. The Molecular Genetics of Viruses.

23. Molecular Pathogenesis.

24. Viral Bioinformatics and Beyond.

25. Viruses and the Future – Promises and Problems.

Appendix: Resource Center.

Index

ISBN-13碼 : 9781405147156

出版日期 : 2007

版次 : 3

書系代碼 : 03018

作者 : Edward K Wagner．Martinez J Hewlett．David C Bloom．David Camerini

開數 : 菊8開

頁數 : 550

裝訂 : 平裝

印刷 : 彩色

定價 : 1800

教學資源 : 僅供採用本書為授課教科書之老師申請