內容簡介
Organic Chemistry by Fox and Whitesell is the pioneer in the mechanistic approach. Now in its third volume, this classic and proven pedagogy provides a much better basis for students to retain a knowledge base and extend it to practical applications in other areas of science. The mechanistic approach groups chemical reactions according to how the sequence of changes occurs- their common mechanisms- rather than by functional groups (what category- alcohols, amines, alkenes, etc.). Where appropriate, the text subdivides information based on functional groups. The text covers ALL of basic organic chemistry in the first 14 chapters and reviews the reactions covered in these chapters in chapter 15 on multi-step synthesis. The text also contains extensive coverage of both industrial and biological polymers, and describes molecular basis for drug action.
序言
As in previous editions, the new third edition of Organic Chemistry succeeds in providing students with an accessible framework for understanding the complex material covered in this course. Fox and Whitesell are pioneers of the mechanistic approach, and they utilize this proven and effective pedagogy to equip students with a solid foundation to retain organic chemistry principles and apply them to practical applications in other areas of science.
作者簡介
One of the nation's most distinguished physical organic chemists, Marye Anne Fox is currently Chancellor of the University of California, San Diego. Previously she served as Chancellor of North Carolina State University for 6 years and prior to that was Vice President for research at the University of Texas at Austin. Dr. Fox has published extensively in both chemistry and science policy. She has received numerous teaching awards, including Sigma Xi's Monie Ferst Award, a national honor recognizing her outstanding mentoring of graduate students, and various research awards from professional societies in the United States and abroad. Dr. Fox also holds honorary degrees from universities in France, Northern Ireland, and Spain and has held more than 50 endowed lectureships at universities worldwide. Additionally, she has served on the Executive Committee of the National Academy of Sciences and has been elected to membership in the American Philosophical Society, the President's Council of Advisors on Science and Technology, as a fellow of the American Academy of Arts and Sciences, and as a foreign member of the Royal Academy of Arts and Sciences of Barcelona. She co-chairs the National Research Council's Government-University-Industry Research Roundtable and is chair of the National Association of Land Grant Colleges and Universities' Commission on Food, Environment, and Renewable Resources. Dr. Fox holds a B.S. degree from Notre Dame and earned her Ph.D. from Dartmouth College, both in chemistry.
James K. Whitesell, who is married to Marye Anne Fox, is a member of the Department of Chemistry and Biochemistry at the University of California, San Diego. Previously, he taught at North Carolina State University where he was a Professor of Chemistry. Dr. Whitesell's research interests include stereochemistry, both in a molecular and a supramolecular sense, which is a key element in drug discovery and design. Some of his recent publications include “Influence of Molecular Dipole Interactions on Solid-State Organization”, “Molecular-Crystal Engineering by Shape Mimicry”, and “Directionally Aligned Helical Peptides on Surfaces”. Dr. Whitesell received his B.S. from Pennsylvania State University and his Ph.D. from Harvard University.
目次
Chapter 1 - Structure and Bonding in Alkanes
Chapter 2 - Alkenes, Aromatic Hydrocarbons, and Alkynes
Chapter 3 - Functional Groups Containing Heteroatoms
Chapter 4 - Chromatography and Spectroscopy
Chapter 5 - Stereochemistry
Chapter 6 - Understanding Organic Reactions
Chapter 7 - Mechanisms of Organic Reactions
Chapter 8 - Substitution by Nucleophiles at sp3-Hybridized Carbon
Chapter 9 - Elimination Reactions
Chapter 10 - Addition to Carbon–Carbon Multiple Bonds
Chapter 11 - Electrophilic Aromatic Substitution
Chapter 12 - Nucleophilic Addition and Substitution at Carbonyl Groups
Chapter 13 - Substitution Alpha to Carbonyl Groups: Enolate Anions and Enols as Nucleophiles
Chapter 14 - Skeletal-Rearrangement Reactions
Chapter 15 - Multistep Syntheses
Chapter 16 - Polymeric Materials
Chapter 17 - Naturally Occurring Oxygen-Containing Compounds
Chapter 18 - Naturally Occurring Nitrogen-Containing Compounds
Chapter 19 - Noncovalent Interactions and Molecular Recognition
Chapter 20 - Catalyzed Reactions
Chapter 21 - Cofactors for Biological Reactions
Chapter 22 - Energy Storage in Organic Molecules
Chapter 23 - Molecular Basis for Drug Action
