Immunogenomics & Human Disease 2006

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Immunogenomics & Human Disease 2006

內容簡介

This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.


作者簡介

András Falus is Chairman of the Department of Genetics, Cell and Immunobiology at Semmelweis Medical University in Budapest and a Member of the Hungarian Academy of Sciences. He has written and edited several books on immunology, particularly histamine.


目次

1. Genotyping Methods and Disease Gene Identification (Ramón Kucharzak and Ivo Glynne Gut). 
2. Glycomics and the Sugar Code: Primer to their Structural Basis and Functionality (Hans-Joachim Gabius). 
3. Proteomics in Clinical Research: Perspectives and Expectations (Ivan Lefkovits, Thomas Grussenmeyer, Peter Matt, Martin Grapow, Michael Lefkovits and Hans-Reinhard Zerkowski). 
4. Chemical Genomics: Bridging the Gap Between Novel Targets and Small Molecule Drug Candidates. Contribution to Immunology (György Dormán, Takenori Tomohiro, Yasumaru Hatanaka and Ferenc Darvas). 
5. Genomic and Proteomic Analysis of Activated Human Monocytes (Ameesha Batheja, George Ho, Xiaoyao Xiao, Xiwei Wang and David Uhlinger). 
6. Bioinformatics as a Problem of Knowledge Representation: Applications to Some Aspects of Immunoregulation (Sándor Pongor and András Falus). 
7. Immune Responsiveness of Human Tumours (Ena Wang and Francesco M. Marincola). 
8. Chemokines Regulate Leukocyte Trafficking and Organ-specific Metastasis (Andor Pivarcsi, Anja Mueller and Bernhard Homey). 
9. Towards a Unified Approach to New Target Discovery in Breast Cancer: Combining the Power of Genomics, Proteomics and Immunology (Laszlo G. Radvanyi, Bryan Hennessy, Kurt Gish, Gordon Mills and Neil Berinstein). 
10. Genomics and Functional Differences of Dendritic Cell Subsets (Peter Gogolak and Eva Rajnavölgyi). 
11. Systemic Lupus Erythematosus: New Ideas for Diagnosis and Treatment (Sandeep Krishnan and George C. Tsokos). 
12. Immunogenetics of Experimentally Induced Arthritis (Tibor T. Glant and Vyacheslav A. Adarichev). 
13. Synovial Activation in Rheumatoid Arthritis (Lars C. Huber, Renate E. Gay and Steffen Gay). 
14. T Cell Epitope Hierarchy in Experimental Autoimmune Models (Edit Buzas). 
15. Gene–Gene Interactions in Immunology as Exemplified by Studies on Autoantibodies against 60 kDa Heat-shock Protein  (Zoltán Prohászka). 
16. Histamine Genomics and Metabolomics (Andras Falus, Hargita Hegyesi, Susan Darvas, Zoltan Pos and Peter Igaz). 
17. The Histamine H4 Receptor: Drug Discovery in the Post-genomic Era (Niall O'Donnell, Paul J. Dunford and Robin L. Thurmond). 
18. Application of Microarray Technology to Bronchial Asthma (Kenji Izuhara, Kazuhiko Arima, Sachiko Kanaji, Kiyonari Masumoto and Taisuke Kanaji). 
19. Genomic Investigation of Asthma in Human and Animal Models (Csaba Szalai). 
20. Primary Immunodeficiencies: Genotype–Phenotype Correlations (Mauno Vihinen and Anne Durandy). 
21. Transcriptional Profiling of Dendritic Cells in Response to Pathogens (Maria Foti, Francesca Granucci, Mattia Pelizzola, Norman Pavelka, Ottavio Beretta, Caterina Vizzardelli, Matteo Urbano, Ivan Zanoni, Giusy Capuano, Francesca Mingozzi and Paola Ricciardi-Castagnoli). 
22. Parallel Biology: a Systematic Approach to Drug Target and Biomarker Discovery in Chronic Obstructive Pulmonary Disease (Laszlo Takacs). 
23. Mycobacterial Granulomas: a Genomic Approach (Laura H. Hogan, Dominic O. Co and Matyas Sandor). 
Index.

ISBN-13碼 : 9780470015308
ISBN-10碼 : 0470015306
出版日期 : 2006
書系代碼 : 23106
作者 : András Falus
開數 : 18開
頁數 : 548
裝訂 : 精裝
定價 : NT$2,350.00
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