內容簡介
The textbook that has defined the field of immunology since 1984 is now in its thoroughly revised and updated Sixth Edition. This comprehensive, up-to-date text will be of interest to graduate students,post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.
This edition features expanded coverage of regulatory T cells, innate immunity, and dendritic cells. Additional chapters on cytokines are also included.
A companion Website offers the fully searchable text, plus all illustrations in full color and comprehensive lists of references.
目次
SECTION I: INTRODUCTION
1. The Immune System / William E. Paul
SECTION II: ORGANIZATION AND EVOLUTION OF THE IMMUNE SYSTEM
2. Lymphoid Tissues and Organs / Eitan M. Akirav, Shan Liao, and Nancy H. Ruddle
3. Evolution of the Immune System / Martin F. Flajnik and Louis Du Pasquier
SECTION III: IMMUNOGLOBULINS AND B LYMPHOCYTES
4. Immunoglobulins: Structure and Function / Harry W. Schroeder, Jr., David Wald, and Neil S. Greenspan
5. Antigen–antibody Interactions and Monoclonal Antibodies / Jay A. Berzofsky, Ira J. Berkower, and Suzanne L. Epstein
6. Immunoglobulins: Molecular Genetics / Edward Max
7. B Lymphocyte Development and Biology / Richard R. Hardy
8. B Lymphocyte Signaling Mechanisms and Activation / Anthony L. DeFranco
9. B Lymphocyte Biology / Michael McHeyzer-Williams
SECTION IV: T LYMPHOCYTES
10. T Cell Antigen Receptors / Mark M. Davis and Yueh-Hsiu Chien
11. T Lymphocyte Signaling Mechanisms and Activation / Gary A. Koretzky
12. Development of T Cells / Ellen V. Rothenberg and Mary A. Yui
13. Peripheral T Lymphocyte Responses and Function / Steven L. Reiner
SECTION V: THE INTERSECTION OF INNATE AND ADAPTIVE IMMUNITY
14. The Innate Immune System / Ruslan Medzhitov
15. Dendritic Cells / Muriel Moser
16. Natural Killer Cells / Wayne M. Yokoyama
17. NKT Cells and Other Innatelike T and B Lineages / Albert Bendelac
18. Macrophages and Phagocytosis / Siamon Gordon
19. Major Histocompatibility Complex (MHC) Molecules: Structure, Function, and Genetics / David H. Margulies, Kannan Natarajan, Jamie Rossjohn, and James McCluskey
20. Cell Biology of Antigen Processing and Presentation / L´elia Delamarre and Ira Mellman
SECTION VI: REGULATION AND EFFECTOR FUNCTIONS OF THE IMMUNE RESPONSE
21. Immunogenicity and Antigen Structure / Jay A. Berzofsky and Ira J. Berkower
22. Fc Receptors and Their Role in Immune Regulation and Inflammation / Jeffrey V. Ravetch and Falk Nimmerjahn
23. Type I Cytokines and Interferons and Their Receptors / Warren J. Leonard
24. Interleukin-1 Family of Ligands and Receptors / Charles A. Dinarello
25. TNF-Related Cytokines in Immunity / Carl F. Ware
26. Chemokines / Philip M. Murphy
27. Programmed Cell Death / Nicolas Bid`ere, Helen C. Su, and Michael J. Lenardo
28. Immunologic Memory / Stephen P. Schoenberger and Shane Crotty
29. Immunologic Tolerance / Ronald H. Schwartz
30. Regulatory/Suppressor T Cells / Ethan M. Shevach
31. The Mucosal Immune System / Hiroshi Kiyono, Jun Kunisawa, Jerry R. McGhee, and Jiri Mestecky
32. Neural Immune Interactions / Jeanette. I. Webster Marketon and Esther M. Sternberg
33. Complement / Cornelia Speth, Wolfgang M. Prodinger, ¨ Reinhard Wurzner, Heribert Stoiber, and Manfred P. Dierich
34. Cytotoxic T Lymphocytes / R. Chris Bleackley
SECTION VII: IMMUNITY TO INFECTIOUS AGENTS
35. The Immune Response to Parasites / David L. Sacks, Alan Sher, Eleanor M. Riley, and Thomas A. Wynn
36. Immunity to Viruses / Hildegund Ertl
37. Immune Responses to Intracellular Bacteria / Eric Pamer
38. Immunity to Extracellular Bacteria / Jeffrey N. Weiser and Moon H. Nahm
39. Immunology of HIV Infection / Norman L. Letvin
40. Vaccines / G.J.V. Nossal
SECTION VIII: IMMUNOLOGIC MECHANISMS IN DISEASE
41. Systemic Autoimmunity / Betty Diamond
42. Organ-Specific Autoimmunity / Matthias G. von Herrath and Dirk Homann
43. Immunological Mechanisms of Allergic Disease / Marsha Wills-Karp
44. Transplantation Immunology / Megan Sykes, Kathryn Wood, and David H. Sachs
45. Tumor Immunology / Nicholas P. Restifo, Paul F. Robbins, and Steven A. Rosenberg
46. Primary Immunodeficiency Diseases / Rebecca H. Buckley
Index
ISBN-13碼 :
9780781765190
ISBN-10碼 :
0781765196
出版日期 :
2008
版次 :
6
書系代碼 :
23113
作者 :
William E. Paul
開數 :
18開
頁數 :
1632
裝訂 :
精裝
印刷 :
黑白
定價 :
NT$5980.00
