Biochemistry and Molecular Biology 5/e 2014

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Biochemistry and Molecular Biology 5/e 2014

內容簡介

Now in its fifth edition, Biochemistry and Molecular Biology features a new author team, who have retained the much-praised clarity of previous editions, while adding a greater focus on biomedical issues and incorporating a discussion of recent developments in research.
 
A new chapter on the general principles of nutrition emphasizes the key principles underlying complex metabolic pathways, enabling students to appreciate an integrated view of human metabolism and nutrition. The fifth edition also features a new chapter on the control of gene expression reflects our increasing understanding of the importance and power of gene regulation.
 
Presented in a broader cellular context and featuring an integrated approach covering both biochemistry and molecular biology, this text is complemented by frequent diagrams. It is the perfect introduction for any student new to the subject.
 
New to this Edition
• A new Chapter 9, "General Principles of Nutrition," enables students to understand the key principles underlying complex metabolic pathways
• A new Chapter 26, "Control of Gene Expression" reflects the increasing emphasis on gene regulation in contemporary research
• A strengthened biomedical focus provides extra context to the processes and concepts being described
• Two new authors, Alison Snape and Despo Papachristodou, bring additional teaching and research experience in biochemistry and molecular biology to the book

作者簡介

Alison Snape is Programme Director for the BSc in Biomedical Science and Lecturer in Biochemistry at King's College London. Her research interests include gene expression and differentiation in early embryonic development.
 
Despo Papachristodoulou is Senior Lecturer in Biochemistry and Head of Preclinical Medicine at King's College London School of Medicine. Her research interests include diabetes and diabetic complications, insulin metabolism, intermediary metabolism, nutrition, medical education, and curriculum development.
 
The late William H. Elliott was Head of the Biochemistry department at the University of Adelaide.
 
Prior to her retirement, Daphne C. Elliott was a senior lecturer at Flinders University. She is one of the first Australian women to win the prestigious Commonwealth Scholarship.

目次

PART 1: BASIC CONCEPTS OF LIFE
1. The basic molecular themes of life
2. Cells and viruses
3. Energy considerations in biochemistry
PART 2: STRUCTURE AND FUNCTION OF PROTEINS AND MEMBRANES
4. The structure of proteins
5. Methods in protein investigation
6. Enzymes
7. The cell membrane and membrane proteins
8. Muscle contraction, the cytoskeleton, and molecular motors
PART 3: METABOLISM AND NUTRITION
9. General principles of nutrition
10. Food digestion, absorption, and distribution to the tissues
11. Mechanisms of transport, storage, and mobilization of dietary components
12. Principles of energy release from food
13. Glycolysis, the TCA cycle, and the electron transport system
14. Energy release from fat
15. An alternative pathway of glucose oxidation. The pentose phosphate pathway
16. Synthesis of glucose (gluconeogenesis)
17. Synthesis of fat and related compounds
18. Nitrogen metabolism: amino acid metabolism
19. Nitrogen metabolism: nucleotide metabolism
20. Mechanisms of metabolic control and their applications to metabolic integration
21. Raising electrons of water back up the energy scale - photosynthesis
PART 4: INFORMATION STORAGE AND UTILIZATION
22. The genome
23. DNA synthesis, repair, and recombination
24. Gene transcription
25. Protein synthesis and controlled protein breakdown
26. Control of gene expression
27. Protein sorting and delivery
28. Manipulating DNA and genes
PART 5: CELLS AND TISSUES
29. Cell signalling
30. The cell cycle, cell division and cell death
31. Cancer
PART 6: PROTECTIVE MECHANISMS AGAINST DISEASE
32. Special topics: blood clotting, xenobiotic metabolism, reactive oxygen species
33. The immune system

ISBN-13碼 : 9780199609499
ISBN-10碼 : 0199609497
出版日期 : 2014
版次 : 5
書系代碼 : 9780199609499
作者 : Despo Papachristodoulou.Alison Snape.William H. Elliott.Daphne C. Elliott
開數 : 菊8開
頁數 : 624
裝訂 : 平裝
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