1 Introduction to the Immune System

    Nomenclature, General Properties, and Components

2 Innate Immunity

    The Early Defense Against Infections

3 Antigen Capture and Presentation to Lymphocytes

    What Lymphocytes See

4 Antigen Recognition in the Adaptive Immune System

    Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires

5 T Cell-Mediated Immunity

    Activation of T Lymphocytes

6 Effector Mechanisms of T Cell-Mediated Immunity

    Functions of T Cells in Host Defense

7 Humoral Immune Responses

    Activation of B Lymphocytes and Production of Antibodies

8 Effector Mechanisms of Humoral Immunity

    Elimination of Extracellular Microbes and Toxins

9 Immunological Tolerance and Autoimmunity

    Self-Nonself Discrimination in the Immune System and Its Failure

10 Immune Responses Against Tumors and Transplants

    Immunity to Noninfectious Transformed and Foreign Cells

11 Hypersensitivity

    Disorders Caused by Immune Responses

12 Congenital and Acquired Immunodeficiencies

    Diseases Caused by Defective Immunity

Selected Readings

Appendix I Glossary

Appendix II Cytokines

Appendix III Principal Features of Selected CD Molecules

APPENDIX IV Clinical Cases