An Introduction to Medicinal Chemistry 6/e 2018

1: Drugs and drug targets - an overview
Part A Drug targets - structure and function
2: Protein structure and function
3: Enzymes: structure and function
4: Receptors: structure and function
5: Receptors and signal transduction
6: Nucleic acids: structure and function
Part B Pharmacodynamics and pharmacokinetics
7: Enzymes as drug targets
8: Receptors as drug targets
9: Nucleic acids as drug targets
10: Miscellaneous drug targets
11: Pharmacokinetics and related topics
Case study 1: Statins
Part C Drug discovery, design, and development
12: Drug discovery: finding a lead
13: Drug design: optimizing target interactions
14: Drug design: optimizing access to the target
15: Getting the drug to market
Case study 2: The design of ACE inhibitors
Case study 3: Artemisinin and related antimalarial drugs
Case study 4: The design of oxamniquine
Part D Tools of the trade
16: Combinatorial synthesis
17: Computers in medicinal chemistry
18: Quantitative structure-activity relationships (QSAR)
Case study 5: De novo design of a thymidylate synthase inhibitor
Part E Selected topics in medicinal chemistry
19: Antibacterial agents
20: Antiviral agents
21: Anticancer agents
22: Cholinergics, anticholinergics, and anticholinesterases
23: Drugs acting on the adrenergic nervous system
24: Opioid analgesics
25: Antiulcer agents
26: Cardiovascular drugs
Case study 6: Steroidal anti-inflammatory agents
Case Study 7: Design of a novel antidepressant
Case Study 8: The design and development of aliskiren
Case Study 9: Factor Xa inhibitors
Case Study 10: Reversible inhibitors of HCV NS3-4A protease